TNF-α in Cancer Treatment: Molecular Insights, Antitumor Effects, and Clinical Utility

TNF-α in Cancer Treatment: Molecular Insights, Antitumor Effects, and Clinical Utility Remco van Horssen, Timo L. M. ten Hagen, Alexander M. M. Eggermont Oncologist 2006; 11: 397-408 Author Information and Disclosures Target Audience: Physicians who wish to advance their current knowledge of clinical cancer medicine in sarcomas and are involved in providing patient care in a cancer care environment. Method of Physician Participation: Read course materials, complete course quiz and evaluation form (required). Learning Objectives After completing this course, the reader should be able to: Discuss the role of TNF-α in cancer survival and apoptosis. Describe the mechanism of chemotherapy potentiation by TNF-α. Explain the selective targeting of tumor vasculature by TNF-α. Discuss TNFR-1 and TNFR-2 signaling. The NIH/FAES designates this educational activity for a maximum of 1 AMA PRA Category 1 Credit™. Physicians should only claim credit commensurate with the extent of their participation in the activity.

CME Activity Information Accreditation CME Instructions For Credit Privacy Statement Hardware/Software Requirements Release Date: Apr. 13, 2006 Most Recent Review: May 15, 2007* Most Recent Update: June 12, 2007 Date Credit Expires: Apr. 13, 2008 Time to Complete: 1 hour Medium: Internet Online *Click here to learn more about our review process.