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The Role of Bevacizumab in the Treatment of Non-Small Cell Lung Cancer: Current Indications and Future Developments

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CME Activity Information
Release Date: October 25, 2007
Most Recent Review: October 25, 2007*
Most Recent Update: October 25, 2007
Date Credit Expires: October 25, 2009
Time to Complete: 1 hour
Medium: Internet Online
*Click here to learn more about our review process.
Instructions for Participation

  1. Read the following information before beginning the educational activity and click the "Take this course" link at the bottom of the page
  2. Study the educational activity
  3. Complete the CME quiz and evaluation
  4. After successful completion of the CME quiz and evaluation, you will receive the credit or participation certificate

    *The CME quiz and evaluation must be completed by October 25, 2009, in order to receive the credit or participation certificate.



Target Audience
Physicians who wish to advance their current knowledge of clinical cancer medicine in lung cancer and are involved in providing patient care in a cancer care environment.

Learning Objectives
After completing this course, the reader should be able to:
  1. Describe the main clinical trials of bevacizumab combined with chemotherapy in the treatment of advanced NSCLC.
  2. Describe the main clinical trials of bevacizumab combined with other targeted therapies in the treatment of advanced NSCLC.
  3. Describe some ongoing trials of bevacizumab in the treatment of NSCLC and try to define future developments of bevacizumab in this clinical setting.
Accreditation and Credit Designation
This activity has been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of the School of Medicine of The University of North Carolina at Chapel Hill and The Oncologist. The School of Medicine of The University of North Carolina at Chapel Hill is accredited by the ACCME to provide continuing medical education for physicians.

The School of Medicine of The University of North Carolina at Chapel Hill designates this educational activity for a maximum of 1.00 AMA PRA Category 1 Credit™. Physicians should only claim credit commensurate with the extent of their participation in the activity.

Disclosure Policy

In compliance with the Standards of the ACCME, it is the policy of the School of Medicine of The University of North Carolina at Chapel Hill to ensure balance, independence, objectivity, and scientific rigor in all of its educational activities and to include information free of commercial bias and based on the best evidence available. All individuals in a position to influence the content of this activity have disclosed relevant financial interests or relationships of their own, their spouse/partner, or their worksite, with manufacturers or providers of commercial products, services, technology, or programs; and disclosed relationships with current non-governmental supporters of the activity. The faculty and planners have indicated that they have no relevant commercial relationships. For a list of the faculty and planners, please visit the Editorial Board online at http://cme.theoncologist.com/misc/edboard.shtml.

All information is submitted and reviewed and found to be scientifically rigorous, based on the best available evidence, fair and balanced, and free of commercial bias. All the recommendations involving clinical medicine in this CME activity are based on evidence that is accepted within the profession of medicine as adequate justification for their indications and contraindications in the care of patients. All scientific research referred to, reported or used in CME in support or justification of a patient care recommendation conforms to the generally accepted standards of experimental design, data collection and analysis.

Any potential conflicts of interests are resolved via The Oncologist's anonymous peer review process: http://theoncologist.alphamedpress.org/misc/ifora.shtml. All manuscripts are reviewed by the Editorial Board with ad hoc assistance from two or more external experts in the field. All final publication decisions are made by the Editorial Board. The acceptance of a manuscript is based on its originality and importance to the field as assessed by the Editors.

Author Disclosure(s)
Cesare Gridelli, M.D.

Credentials: Division of Medical Oncology, “S.G. Moscati” Hospital, Contrada Amoretta, 83100 Avellino, Italy. Telephone: 39-0825-203573; Fax: 39-0825-203556; E-mail: cgridelli{at}libero.it.
Disclosures: The author has indicated no relevant commercial relationships.

Paolo Maione, M.D.

Credentials: Division of Medical Oncology, “S.G. Moscati” Hospital, Avellino, Italy.
Disclosures: The author has indicated no relevant commercial relationships.

Antonio Rossi, M.D.

Credentials: Division of Medical Oncology, “S.G. Moscati” Hospital, Avellino, Italy.
Disclosures: The author has indicated no relevant commercial relationships.

Filippo De Marinis, M.D.

Credentials: I Division of Oncological Pneumology, Department of Lung Diseases, San Camillo-Forlanini Hospitals, Roma, Italy.
Disclosures: The author has served as a consultant for Roche.

Commercial Support
Non-governmental supporters of this activity: Abraxis BioScience, AstraZeneca, Bristol-Myers Squibb Oncology, Merck, Pfizer, and sanofi-aventis

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