Review: Implications of In Vitro Research on the Effect of Radiotherapy and Chemotherapy Under Hypoxic Conditions

Review: Implications of In Vitro Research on the Effect of Radiotherapy and Chemotherapy Under Hypoxic Conditions An Wouters, Bea Pauwels, Filip Lardon, Jan B. Vermorken Oncologist 2007; 12: 690-712 Author Information and Disclosures Target Audience: Physicians who wish to advance their current knowledge of clinical cancer medicine in symptom management and are involved in providing patient care in a cancer care environment. Method of Physician Participation: Read course materials, complete course quiz and evaluation form (required). Learning Objectives After completing this course, the reader should be able to: Argue why hypoxic regions in solid tumors often contain viable cells that are intrinsically more resistant to treatment with radiotherapy or chemotherapy. Describe how exposure of cells or cell lines to hypoxic conditions has major implications on multiple intracellular pathways. Evaluate the importance of investigating chemoradiotherapy combinations in vitro under both normoxic and hypoxic conditions. The NIH/FAES designates this educational activity for a maximum of 1 AMA PRA Category 1 Credit™. Physicians should only claim credit commensurate with the extent of their participation in the activity.

CME Activity Information Accreditation CME Instructions For Credit Privacy Statement Hardware/Software Requirements Release Date: Jun. 29, 2007 Most Recent Review: Jun. 29, 2007* Most Recent Update: Jun. 29, 2007 Date Credit Expires: Jun. 29, 2009 Time to Complete: 1 hour Medium: Internet Online *Click here to learn more about our review process.

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